A study conducted by researchers from the University of Jaén and the Bellvitge Institute for Biomedical Research, examined the effects of tyrosol on Caenorhabditis elegans worms with various forms of parkinsonism.
The research team found that tyrosol-treated worms enjoyed a significantly longer lifespan of approximately 21,33 days than untreated worms whose average lifespan was only 18,67 days.
The researchers concluded that tyrosol delays the neurodegeneration of worms and reduces oxidative stress. It also appears to induce the expression of several protective genes in a particular form of parkinsonism.
It was also noted that tyrosol-treated worms benefited from 80% of intact dopaminergic neurons at two weeks of age compared to 45,33% of those not treated. This was an important discovery since the loss of these neurons is a trademark of Parkinson's disease.
Overall results suggest that tyrosol treatment had an effective antioxidant effect, significantly increasing the expression of some proteins, including heat shock proteins, which are known to help cells protect themselves from damage.
In a previous study by the same research team, tyrosol was found to delay aging, increase lifespan and reduce cell stress markers.